
The Genome Stability and Editing Laboratory
RECENT PUBLICATIONS
Complete list of publications:
* First author(s)
# Corresponding author(s)
Members of the lab
2022
Title: CRISPR-based Genome Editing Through the Lens of DNA Repair.
Authors: Nambiar T*, Baudrier L, Billon P#, Ciccia A#. Molecular Cell. [Download the PDF]. Journal.
2021
Title: A detection method for the capture of genomic signatures: From disease diagnosis to genome editing.
Authors: Benamozig O*, Baudrier L, Billon P#. Methods in Enzymology. [Download the PDF]. Pubmed.
2020
Title: Detection of Marker-Free Precision Genome Editing and Genetic Variation through the Capture of Genomic Signatures.
Authors: Billon P*, Nambiar TS, Hayward SB, Zafra MP, Schatoff EM, Oshima K, Dunbar A, Breinig M, Park YC, Ryu HS, Tschaharganeh DF,
Levine RL, Baer R, Ferrando A, Dow LE, Ciccia A#. Cell Reports. 30(10):3280-3295.e6. [Download the PDF]. Pubmed.
- Article recommended on Faculty Opinions (formerly F1000)
- Plasmids are available on Addgene
2019
Title: Stimulation of CRISPR-mediated homology-directed repair by an engineered RAD18 variant.
Authors: Nambiar TS*, Billon P, Diedenhofen G, Hayward SB, Taglialatela A, Cai K, Huang JW, Leuzzi G, Cuella-Martin R, Palacios A, Gupta A, Egli D, Ciccia A#. Nature Commun. 10(1):3395. [Download the PDF]. Pubmed.
- Plasmids are available on Addgene.
2018
Title: Phospho-dependent recruitment of the yeast NuA4 acetyltransferase complex by MRX at DNA breaks regulates RPA dynamics during resection.
Authors: Cheng X*, Jobin-Robitaille O*, Billon P, Buisson R, Niu H, Lacoste N, Abshiru N, Côté V, Thibault P, Kron SJ, Sung P, Brandl CJ, Masson JY, Côté J#. Proc Natl Acad Sci U S A. 115(40):10028-10033. [Download the PDF]. Pubmed.
2017
Title: CRISPR-Mediated Base Editing Enables Efficient Disruption of Eukaryotic Genes through Induction of STOP Codons.
Authors: Billon P*, Bryant EE*, Joseph SA, Nambiar TS, Hayward SB, Rothstein R, Ciccia A#. Mol Cell. 67(6):1068-1079.e4. [Download the PDF]. Pubmed.
- Article recommended on Faculty Opinions (formerly F1000)
- Website for the design of gRNAs for iSTOP (base editing)
- Plasmids available on Addgene
- Scripts are available on Github
Title: Novel mechanism of PCNA control through acetylation of its sliding surface.
Authors: Billon P# and Côté J#. Mol Cell Oncol. 4(2):e1279724. [Download the PDF]. Pubmed.
Title: Acetylation of PCNA Sliding Surface by Eco1 Promotes Genome Stability through Homologous Recombination.
Authors: Billon P*, Li J, Lambert JP, Chen Y, Tremblay V, Brunzelle JS, Gingras AC, Verreault A, Sugiyama T, Couture JF, Côté J#.
Mol Cell 65(1):78-90. [Download the PDF]. Pubmed.
2013
Title: Precise deposition of histone H2A.Z in chromatin for genome expression and maintenance.
Authors: Billon P* and Côté J#. Biochim Biophys Acta. 1819(3-4):290-302. [Download the PDF]. Pubmed.