The Genome Stability and Editing Laboratory
LATEST NEWS
September, 2023
THE LAB IS FEATURED IN THE AVENUE MAGAZINE!
Pierre was interviewed by the September/October 2023 edition of the Avenue Magazine for the lab recent work on genome editing and cancer.
Find the article here (page 141)
Our recent work has been highlighted in the Avenue Magazine!
June, 2023
THE LAB WELCOMES DEWUNI AS A SUMMER STUDENT!
We are excited to introduce Dewuni De Silva, a highly talented Undergraduate Student from the Biomedical Sciences Program at the University of Calgary, who has joined our laboratory for the summer! Dewuni will be at the forefront of expanding the boundaries of prime editing-based approaches.
Dewuni's ambitious goal is to advance the potential of the emerging prime editing-based tools for the treatment of human genetic diseases and towards combating human cancers.
We look forward to witnessing the remarkable discoveries and development that you will make during your journey with us!
Discover our Team Members: here
Want to join us? Follow the requirements on how to apply: here
We are excited to announce that Dewuni De Silva has joined our lab for the summer
May, 2023
SHRIYA AND JETHRO RECEIVE PRESTIGIOUS SCHOLARSHIPS!
We are thrilled to announce that Shriya and Jethro have received highly competitive scholarships!
We are proud to announce that two members of our team, Shriya and Jethro, have been distinguished with two prestigious and highly competitive Scholarships for their leadership and academic achievements!
Shriya was recognized for her leadership skills and stellar performance during Undergrad! She is the recipient of the Cumming School of Medicine Graduate Scholarship
For his outstanding work as a M.Sc in our lab, Jethro was awarded the Recruitment Scholarship to further his academic journey as he transitions to his Ph.D. in our lab!
We are thrilled that your hard work is being acclaimed by our scientific community through these prestigious scholarships! More success are coming for you!
Congratulations and continue to make us proud of you!
May, 2023
JEREMIE JOINS PERELMAN SCHOOL OF MEDICINE
Jérémie has joined the Song Lab in the vibrant community at the Perelman School of Medicine. We wish you best of luck in your new scientific adventure!
We are happy to announce that Jérémie Fages has joined the Children's Hospital in Philadelphia as a postdoc
March, 2023
NEXT-GENERATION CRISPR TECHNOLOGIES: REVOLUTIONIZING HEALTHCARE - WATCH OUR TED-STYLE TALK AND PANEL DISCUSSION
We are excited to share a TED-style talk and panel discussion on the groundbreaking impact of next-generation CRISPR technologies on our health and society!
During the talk, delivered live at the Cracking the Cancer Code event, Pierre explored how scientists have gone from observing mysterious DNA elements in microbe genomes to creating life-changing medicines. The panel also discusses the future of gene therapy and next-generation genome editing, and how these technologies will continue to revolutionize healthcare.
Watch the event here
Pierre discusses the transformative power of CRISPR and its potential impact on the future of healthcare
February, 2023
INTERNATIONAL DAY OF WOMEN IN SCIENCE
Today the world is celebrating women scientists!
Congratulations to all the women scientists in the world! Science is better and stronger with you.
Thank you for what all the women in the lab, we are honored and privileged to work everyday with such powerful women in our lab!
January, 2023
SHRIYA JOINS OUR LAB!
We are excited to announce that Shriya Iyer has joined our lab for her M.Sc studies!
Shriya earned her B.Sc from Amity University in UAE. Shriya excelled academically, consistently ranking at the top of her classes with almost exclusively A+ and A grades in all courses! Moreover, for her impressive Undergraduate honor thesis, Shriya was one of only three students to earn a perfect GPA of 10/10 in the Department of approximately 150 students.
Shriya's creativity and high productivity have resulted in the publication of 5 articles on nanotechnologies, which can be read here.
With her outstanding leadership, Shriya has also received a prestigious international award from the World Expo Organisation in Dubai on the theme "connecting minds, creating the future". Shriya was recognized among >50,000 participants from 192 countries.
In the lab, Shriya is studying the interplay between DNA damage repair mechanisms and precision genome editing technologies.
We are excited to have you in our lab. Welcome, Shriya!
Want to join the lab? Apply here
January, 2023
CIHR FUNDS GROUNDBREAKING CLINICAL TRIAL IN COLLABORATION WITH DR. NICOLA WRIGHT
Our collaboration with Dr. Nicola Wright to start a base editing clinical trial has been funded by the CIHR!
We are thrilled to announce that our collaboration with Dr. Nicola Wright, to conduct a clinical trial using base editing has been funded by the CIHR! Dr. Wright aims to treat patients in Calgary suffering from C3delta SCID disorder.
We are very excited to be part of this exciting collaboration led by Dr. Wright, which will pave the way to the development of a unique framework for the correction of a wide range of genetic diseases in Canada!
Discover more about our recently published work on base editing here, and apply (following these guidelines) if you want to become part of our team.
Click here to read the press release by the Government of Canada.
December, 2022
A FIRST CANCER PATIENT TREATED WITH BASE EDITED T-CELLS
Base edited T-cells cure a 13-year-old cancer patient!
An incredible news has shaken the world!
Researchers have successfully used engineered T cells to eliminate cancer in a 13-year-old girl diagnosed with T-cell acute lymphoblastic leukemia. The team used base editing to inactivate the CD7 and TRBC genes by introducing premature STOP codons, which effectively shut off the genes. The injection of base edited T-cells in the patient was successful in eliminating the cancer!
In 2017, our team demonstrated that eukaryotic genes can be inactivated by introducing premature STOP codons using base editing (read our original publication here). We are excited that our work could contribute to this extraordinary news! Congratulations to all the researchers in the world who are working tirelessly to develop and enhance base editing to make this happen!
Some news articles: